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Inflammasomes and pyroptosis

Here we focus on understanding the inflammatory response, with particular emphasis on NLRs (Nucleotide-binding domain and Leucine-rich repeat containing Receptors) mechanisms during infection, autoimmunity, chemotherapy and tumorigenesis. These mechanisms include the production of the pro-inflammatory cytokines, IL-1beta and IL-18 as well as the newly characterized caspase-1 dependent cell death pathway and cell types.

Contact Details

Prof. Motti Gerlic, PhD

Department of Clinical Microbiology and Immunology 
Sackler School of Medicine
Tel Aviv University

Tel Aviv 69978


Phone (Office):+972-3-6409400

Phone (Lab):+972-3-6409069

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